A-factor
naturalproductmech:mibig-60e3158633 MINTED SEEDED
Structure
| Standard InChIKey | REAWNMHCBIUKLZ-RWANSRKNSA-N |
|---|---|
| SMILES | CC(C)CCCCC(=O)C1[C@@H](COC1=O)CO |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:119102 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces griseus subsp. griseus NBRC 13350 NCBITaxon:455632 |
SOURCE_ASSERTION | mibig:BGC0000848 | PMID:18375553 |
Occurrences 24
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1099/00221287-129-9-2939 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1128/AEM.71.9.5050-5055.2005 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1128/JB.173.7.2311-2318.1991 |
| Streptomyces coelicolor NCBITaxon:1902 |
LOTUS | DOI:10.1099/00221287-129-9-2939 |
| Streptomyces coelicolor NCBITaxon:1902 |
LOTUS | DOI:10.1128/AEM.71.9.5050-5055.2005 |
| Streptomyces coelicolor NCBITaxon:1902 |
LOTUS | DOI:10.1128/JB.173.7.2311-2318.1991 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1007/BF00264220 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1007/S12275-011-0330-Z |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1039/C2OB06653J |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1046/J.1365-2958.1999.01579.X |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1046/J.1365-2958.2003.03760.X |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1099/00221287-129-9-2939 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1099/13500872-145-5-1161 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1099/MIC.0.027862-0 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1111/J.1365-2958.1994.TB01073.X |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1111/J.1365-2958.2009.06814.X |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1128/JB.00204-08 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1128/JB.171.2.1206-1210.1989 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1128/JB.172.6.3003-3008.1990 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1128/JB.177.21.6083-6092.1995 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1128/JB.177.22.6401-6410.1995 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.1128/JB.185.4.1273-1283.2003 |
| Streptomyces griseus NCBITaxon:1911 |
LOTUS | DOI:10.7164/ANTIBIOTICS.57.218 |
| Streptomyces hygroscopicus NCBITaxon:1912 |
LOTUS | DOI:10.1002/BIT.24965 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000848 | Streptomyces griseus subsp. griseus NBRC 13350 NCBITaxon:455632 |
CLUSTER_UNSTATED | genbank:AP009493.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000848 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/a-factor.yaml, which is generated from the committed inventories. Neither is edited by hand.