A23187
naturalproductmech:mibig-18de581c96 MINTED SEEDED
Structure
| Standard InChIKey | HIYAVKIYRIFSCZ-CYEMHPAKSA-N |
|---|---|
| SMILES | C[C@@H]1CC[C@]2([C@@H](C[C@H]([C@H](O2)[C@H](C)C(=O)C3=CC=CN3)C)C)O[C@@H]1CC4=NC5=C(O4)C=CC(=C5C(=O)O)NC |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA03386, npatlas:NPA003386 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces chartreusis NRRL 3882 NCBITaxon:1079985 |
BGC_CHARACTERIZED | mibig:BGC0000032 | DOI:10.1021/ja00813a047 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/ACS.JNATPROD.6B00996 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/JA00813A047 |
| Streptomyces chartreusis NCBITaxon:1969 |
LOTUS | DOI:10.1128/AAC.01130-10 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000032 | Streptomyces chartreusis NRRL 3882 NCBITaxon:1079985 |
CLUSTER_DEMONSTRATED | genbank:HM452329.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000032 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/a23187.yaml, which is generated from the committed inventories. Neither is edited by hand.