actinorhodin
naturalproductmech:mibig-a2d0f9972a MINTED SEEDED
Structure
| Standard InChIKey | FXTIILIJTTYSLT-WYUUTHIRSA-N |
|---|---|
| SMILES | C[C@@H]1C2=C(C3=C(C(=O)C=C(C3=O)C4=CC(=O)C5=C(C4=O)C(=C6[C@H](O[C@@H](CC6=C5O)CC(=O)O)C)O)C(=C2C[C@H](O1)CC(=O)O)O)O |
| Stereochemistry | fully defined |
| Cross-references | CHEBI:2448, pubchem:5280985 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces coelicolor A3(2) NCBITaxon:100226 |
BGC_CHARACTERIZED | mibig:BGC0000194 | DOI:10.1002/ange.201814172 |
Occurrences 25
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1002/(SICI)1097-0290(19970620)54:6<577::AID-BIT8>3.0.CO;2-G |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/BF00186959 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/BF00339742 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/BF02931330 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00203-004-0669-1 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00203-011-0721-X |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00203-014-1000-4 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00253-007-1184-5 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00253-008-1574-3 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00253-008-1802-X |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00253-009-2368-Y |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00253-009-2412-Y |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00253-012-4129-6 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00253-018-8838-3 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S00438-002-0730-1 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S10295-009-0591-2 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S10482-011-9657-Z |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1007/S10529-012-0987-3 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1016/0014-5793(96)00756-9 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1016/0378-1119(96)00310-1 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1016/B978-0-12-404634-4.00014-0 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1016/J.BBAEXP.2005.06.005 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1016/J.FEBSLET.2005.04.019 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1016/J.GENE.2011.01.005 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1016/J.JMB.2007.12.061 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000194 | Streptomyces coelicolor A3(2) NCBITaxon:100226 |
CLUSTER_DEMONSTRATED | genbank:AL645882.2 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
structure-disagreement — MIBiG cross-references this compound to CHEBI:2448, but ChEBI holds CHEBI:2448 with Standard InChIKey VTIKDEXOEJDMJP-WYUUTHIRSA-N and this record's structure is FXTIILIJTTYSLT-WYUUTHIRSA-N. The skeleton blocks differ, so these are not the same molecule: one of the two databases has the wrong structure for this name. Check which, and report it upstream.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000194 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/actinorhodin.yaml, which is generated from the committed inventories. Neither is edited by hand.