actinospirol B
naturalproductmech:mibig-bbc51c6b2d MINTED SEEDED
Structure
| Standard InChIKey | NPDRNVRLCFOBNU-KRWDZBQOSA-N |
|---|---|
| SMILES | CC1=CC(O)=C2C(=O)O[C@@]3(OC4=CC=CC(C(=O)O)=C4C3=O)C2=C1Br |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA032291, pubchem:156582988 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Actinomadura rubteroloni NCBITaxon:1926885 |
SOURCE_ASSERTION | mibig:BGC0002369 | PMID:28463423 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Actinomadura NCBITaxon:1988 |
LOTUS | DOI:10.1021/ACS.ORGLETT.0C00601 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002369 | Actinomadura rubteroloni NCBITaxon:1926885 |
CLUSTER_UNSTATED | genbank:MTBP01000002.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002369 | MIBIG | 2 |
This page is generated from data/natural_products/polyketides/actinospirol-b.yaml, which is generated from the committed inventories. Neither is edited by hand.