NaturalProductMech

ambruticin

naturalproductmech:mibig-8a5d1c6ab2 MINTED SEEDED

Structure

Standard InChIKeyTYIXBSJXUFTELJ-LQJOTGEPSA-N
SMILESCC[C@@H]1C(=CC[C@@H](O1)/C(=C/[C@H](C)/C=C/[C@H]2[C@H]([C@@H]2/C=C/[C@H]3[C@@H]([C@H](C[C@H](O3)CC(=O)O)O)O)C)/C)C
Stereochemistryfully defined
Cross-referencespubchem:6918547

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Sorangium cellulosum
NCBITaxon:56
SOURCE_ASSERTION mibig:BGC0000014 PMID:17185223

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Sorangium cellulosum
NCBITaxon:56
LOTUS DOI:10.1016/J.CHEMBIOL.2006.10.004
Sorangium cellulosum
NCBITaxon:56
LOTUS DOI:10.7164/ANTIBIOTICS.30.371

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000014 Sorangium cellulosum
NCBITaxon:56
CLUSTER_UNSTATED genbank:DQ897667.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000014MIBIG5

This page is generated from data/natural_products/polyketides/ambruticin.yaml, which is generated from the committed inventories. Neither is edited by hand.