angolamycin
naturalproductmech:mibig-95a6bcd310 MINTED SEEDED
Structure
| Standard InChIKey | KZXDKUWSAVUSKI-JQIJEIRASA-N |
|---|---|
| SMILES | CCC1C(C2C(O2)(/C=C/C(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC3CC(C(C(O3)C)OC4CC(C(C(O4)C)O)(C)O)N(C)C)CC=O)C)C)COC5C(C(C(C(O5)C)O)OC)OC |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:6438267 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces eurythermus NCBITaxon:42237 |
SOURCE_ASSERTION | mibig:BGC0000018 | PMID:18802638 |
| Streptomyces eurythermus NCBITaxon:42237 |
SOURCE_ASSERTION | mibig:BGC0000019 | PMID:18802638 |
Occurrences 0
None cited.
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000018 | Streptomyces eurythermus NCBITaxon:42237 |
CLUSTER_UNSTATED | genbank:EU220288.1 |
| mibig:BGC0000019 | Streptomyces eurythermus NCBITaxon:42237 |
CLUSTER_UNSTATED | genbank:EU232693.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000018, BGC0000019. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000018 | MIBIG | 5 |
| BGC0000019 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/angolamycin.yaml, which is generated from the committed inventories. Neither is edited by hand.