antibiotic HKI 10311129
naturalproductmech:mibig-be71a31d28 MINTED SEEDED
Structure
| Standard InChIKey | MXFCSYMIJBEZOP-AFIPBVKSSA-N |
|---|---|
| SMILES | NC(C(C([C@]12O[C@H]3CC[C@H](O[C@H]4CC[C@H](O)[C@@H](C)O4)[C@@H](C)O3)=O)=C(O)[C@H](O[C@H]5CC[C@H](O[C@H]6CC[C@H](O[C@H]7CC[C@H](O[C@H]8CC[C@H](O)[C@H](C)O8)[C@H](C)O7)[C@H](C)O6)[C@@H](C)O5)C2CC9=CC%10=C(C(C=C(OC)C%10=O)=O)C(O)=C9C1=O)=O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. CS113 NCBITaxon:1982761 |
BGC_CORRELATED | mibig:BGC0001439 | PMID:15326518 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001439 | Streptomyces sp. CS113 NCBITaxon:1982761 |
CLUSTER_CORRELATED | genbank:KZ195574.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001439 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/antibiotic-hki-10311129.yaml, which is generated from the committed inventories. Neither is edited by hand.