NaturalProductMech

arixanthomycin A

naturalproductmech:mibig-7e3e40faee MINTED SEEDED

Structure

Standard InChIKeyIVHSBKKKCDBQDC-IPFCJIHFSA-N
SMILESO=C(C1=CC=CC(O[C@H]2[C@H](OC)[C@@H](OC)[C@H](OC)[C@@H](C)O2)=C1O3)C4=C3C(O)=C(CCC5=C6C(O)=C7C(C[C@@](C)(OC[C@]8([H])C(O)=O)N8C7=O)=C5)C6=C4O
Stereochemistryfully defined

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, saccharide, from MIBiG.

Producer organisms 0

None. The compound has a characterized gene cluster whose host NCBI does not name, which for an uncultured symbiont is the honest state — see the discussion below.

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000200 not named CLUSTER_DEMONSTRATED genbank:KF931341.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

unnamed-producer — No producer claim is written from BGC0000200, which gives NCBITaxon:77133 (uncultured bacterium — shared by every unplaced bacterium), because the taxon names no single organism. The cluster is kept: a characterized locus is an origin assertion whether or not its host has a name, and for a compound from an uncultured symbiont that is the honest state. Name the producer if the primary literature does.

Provenance

Source conceptSourceVersion
BGC0000200MIBIG5

This page is generated from data/natural_products/polyketides/arixanthomycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.