NaturalProductMech

aureothin

naturalproductmech:mibig-a7a97dab7f MINTED SEEDED

Structure

Standard InChIKeyOGUMLESFFBGVOO-VJDLAWOBSA-N
SMILESCC1=C(OC(=C(C1=O)C)OC)[C@H]2CC/C(=C/C(=C/C3=CC=C(C=C3)[N+](=O)[O-])/C)/O2
Stereochemistryfully defined
Cross-referencespubchem:6436188

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces thioluteus
NCBITaxon:66431
BGC_CHARACTERIZED mibig:BGC0000024 PMID:13174453

Occurrences 3

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces orinoci
NCBITaxon:67339
LOTUS DOI:10.1039/B923177C
Streptomyces thioluteus
NCBITaxon:66431
LOTUS DOI:10.1016/S0040-4020(01)92175-1
Streptomyces thioluteus
NCBITaxon:66431
LOTUS DOI:10.1039/B923177C

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000024 Streptomyces thioluteus
NCBITaxon:66431
CLUSTER_DEMONSTRATED genbank:AJ575648.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000024MIBIG5

This page is generated from data/natural_products/polyketides/aureothin.yaml, which is generated from the committed inventories. Neither is edited by hand.