auricin
CHEBI:156301 EXACT SEEDED antimicrobial unspecified
An angucycline-like polyketide discovered in Streptomyces aureofaciens that is only stable at acidic pH.
Structure
| Standard InChIKey | DIESPMSGQPRWLG-VLKAYIDRSA-N |
|---|---|
| SMILES | OC1=CC=CC2=C1C(C([C@]3(O[C@H](C)CC([C@H]3OC4CCC(N(C)C)C(C)O4)=O)O[C@@](C5)([H])[C@]6([H])OC5=O)=C6C2=O)=O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, saccharide, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces aureofaciens NCBITaxon:1894 |
BGC_CHARACTERIZED | mibig:BGC0000201 | PMID:12384301 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces lavendulae subsp. lavendulae NCBITaxon:58340 |
CHEBI | PMID:23373695 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000201 | Streptomyces aureofaciens NCBITaxon:1894 |
CLUSTER_DEMONSTRATED | genbank:KJ396772.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:156301 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000201 | MIBIG | 5 |
| CHEBI:156301 | CHEBI | 3-star |
This page is generated from data/natural_products/polyketides/auricin.yaml, which is generated from the committed inventories. Neither is edited by hand.