azicemicin B
naturalproductmech:mibig-2491bd6a33 MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | UYHQCZYRKRLVIT-UHFFFAOYSA-N |
|---|---|
| SMILES | COC1=C(O)C2=C(C=C1O)C(OC)=C1C(C(=O)CC3CC(O)(CC(=O)C13O)C1CN1)=C2O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA04525 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Kibdelosporangium sp. MJ126-NF4 NCBITaxon:703222 |
SOURCE_ASSERTION | mibig:BGC0000202 | PMID:19928906 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Amycolatopsis NCBITaxon:1813 |
LOTUS | DOI:10.7164/ANTIBIOTICS.48.1148 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000202 | Kibdelosporangium sp. MJ126-NF4 NCBITaxon:703222 |
CLUSTER_UNSTATED | genbank:GU134622.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000202 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/azicemicin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.