NaturalProductMech

betaenone B

naturalproductmech:mibig-b82ffc694c MINTED SEEDED

Structure

Standard InChIKeyPUZNAAVWFXQUDM-HBKHSIGZSA-N
SMILESCC[C@@H](C)[C@@H]1[C@]([C@H]2[C@@H](C[C@@](C[C@@H]2C(=O)[C@@]1(C)O)(C)O)C)(C)C(=O)CCO
Stereochemistryfully defined
Cross-referencespubchem:158750

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Phoma betae
NCBITaxon:1979465
SOURCE_ASSERTION mibig:BGC0001264 PMID:25530455
Parastagonospora nodorum SN15
NCBITaxon:321614
SOURCE_ASSERTION mibig:BGC0002165 PMID:31553484

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Pleospora bjoerlingii
NCBITaxon:318712
LOTUS DOI:10.1021/JA00347A070
Pleospora bjoerlingii
NCBITaxon:318712
LOTUS DOI:10.1039/C39880000600
Pleospora bjoerlingii
NCBITaxon:318712
LOTUS DOI:10.1039/C39900000908
Pleospora bjoerlingii
NCBITaxon:318712
LOTUS DOI:10.1039/P19900001228
Pleospora bjoerlingii
NCBITaxon:318712
LOTUS DOI:10.3186/JJPHYTOPATH.51.219

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0001264 Phoma betae
NCBITaxon:1979465
CLUSTER_UNSTATED genbank:LC011911.1
mibig:BGC0002165 Parastagonospora nodorum SN15
NCBITaxon:321614
CLUSTER_UNSTATED genbank:CH445335.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0001264, BGC0002165. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0001264MIBIG3
BGC0002165MIBIG3

This page is generated from data/natural_products/polyketides/betaenone-b.yaml, which is generated from the committed inventories. Neither is edited by hand.