NaturalProductMech

betaenone C

naturalproductmech:mibig-6a66cb2f42 MINTED SEEDED

Structure

Standard InChIKeyYRYPVWAJOMXOHH-ITBWMFDCSA-N
SMILES[H][C@@](C)(CC)[C@@]1([H])[C@](C)(O)C(=O)[C@@]2([H])C[C@](C)(O)C[C@@H](C)[C@]2([H])[C@@]1(C)C(=O)\C=C/O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA02632, pubchem:71308160, npatlas:NPA002632, pubchem:23244602

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 3

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Phoma betae
NCBITaxon:1979465
SOURCE_ASSERTION mibig:BGC0001264 PMID:25530455
Parastagonospora nodorum SN15
NCBITaxon:321614
SOURCE_ASSERTION mibig:BGC0002165 PMID:31553484
Parastagonospora nodorum SN15
NCBITaxon:321614
SOURCE_ASSERTION mibig:BGC0002165 PMID:31553484

Occurrences 4

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Pleospora bjoerlingii
NCBITaxon:318712
LOTUS DOI:10.1080/00021369.1983.10866069
Pleospora bjoerlingii
NCBITaxon:318712
LOTUS DOI:10.1271/BBB1961.47.2965
Pleospora bjoerlingii
NCBITaxon:318712
LOTUS DOI:10.3186/JJPHYTOPATH.51.219
Theissenia cinerea
NCBITaxon:419774
LOTUS DOI:10.1271/BBB1961.47.2965

Biosynthetic gene clusters 3

AccessionHostLocus evidenceGenome
mibig:BGC0001264 Phoma betae
NCBITaxon:1979465
CLUSTER_UNSTATED genbank:LC011911.1
mibig:BGC0002165 Parastagonospora nodorum SN15
NCBITaxon:321614
CLUSTER_UNSTATED genbank:CH445335.1
mibig:BGC0002165 Parastagonospora nodorum SN15
NCBITaxon:321614
CLUSTER_UNSTATED genbank:CH445335.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0001264, BGC0002165. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0001264MIBIG3
BGC0002165MIBIG3
BGC0002165MIBIG3

This page is generated from data/natural_products/polyketides/betaenone-c.yaml, which is generated from the committed inventories. Neither is edited by hand.