NaturalProductMech

bisvertinolone (spelled bisvertinolon in paper)

naturalproductmech:mibig-2f67f3f6ae MINTED SEEDED

Structure

Standard InChIKeyNWYGQCMFWAOARK-TZCGFCPBSA-N
SMILESC/C=C/C=C/C(=C/1\[C@@H]2[C@@]3(C(=O)/C(=C(\C=C\C=C\C)/O)/C(=O)[C@]([C@]3(O[C@@]2(C(=O)C(=C1O)C)C)O)(C)O)C)/O
Stereochemistryfully defined
Cross-referencespubchem:44584013, npatlas:NPA018406

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Acremonium chrysogenum ATCC 11550
NCBITaxon:857340
SOURCE_ASSERTION mibig:BGC0002190 DOI:10.3390/molecules21060715

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Sarocladium strictum
NCBITaxon:5046
LOTUS DOI:10.1016/S0040-4039(00)77175-9

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002190 Acremonium chrysogenum ATCC 11550
NCBITaxon:857340
CLUSTER_UNSTATED genbank:JPKY01000049.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002190MIBIG2

This page is generated from data/natural_products/polyketides/bisvertinolone-spelled-bisvertinolon-in-paper.yaml, which is generated from the committed inventories. Neither is edited by hand.