NaturalProductMech

brasilinolide A

naturalproductmech:mibig-d12215ceb7 MINTED SEEDED

Structure

Standard InChIKeyMVSIZSYJQDRVAV-LJIRPTLYSA-N
SMILES[H][C@]12C[C@H](O)[C@@H](O)[C@](O)(CC(O)C(C)CCC(O)CC(O)CC(O)C\C=C\C(=O)OC(C(C)C(O)C(C)C(O)C(C)C(C)O[C@@H]3C[C@@H](OC(=O)CCCC)[C@@H](O)[C@@H](C)O3)C(C)C3OC3C(O)CCCC(CC(O)C1)OC(=O)CC(O)=O)O2
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA019615, pubchem:6438451

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Nocardia terpenica
NCBITaxon:455432
SOURCE_ASSERTION mibig:BGC0001381 PMID:26754528

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Nocardia brasiliensis
NCBITaxon:37326
LOTUS DOI:10.7164/ANTIBIOTICS.50.1036

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001381 Nocardia terpenica
NCBITaxon:455432
CLUSTER_UNSTATED genbank:KP161205.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001381MIBIG5

This page is generated from data/natural_products/polyketides/brasilinolide-a.yaml, which is generated from the committed inventories. Neither is edited by hand.