bryostatin
naturalproductmech:mibig-7e373b3a47 MINTED SEEDED
Structure
| Standard InChIKey | NJMZVUZEDLKEGZ-XMADZBCLSA-N |
|---|---|
| SMILES | CCC(C)C(=O)OC1CC2CC(CC(=O)OC(CC3C/C(=C\C(=O)OC)/CC(O3)(C(/C=C/C4C/C(=C/C(=O)OC)/CC(O4)CC(C1(C)C)(O2)O)(C)C)O)C(C)O)O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:6438934 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Candidatus Endobugula sertula NCBITaxon:62101 |
SOURCE_ASSERTION | mibig:BGC0000205 | PMID:17253852 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000205 | Candidatus Endobugula sertula NCBITaxon:62101 |
CLUSTER_UNSTATED | genbank:DQ889942.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000205 | MIBIG | 3 |
This page is generated from data/natural_products/polyketides/bryostatin-2.yaml, which is generated from the committed inventories. Neither is edited by hand.