bryostatin
naturalproductmech:mibig-45bd834dfa MINTED SEEDED
Structure
| Standard InChIKey | MJQUEDHRCUIRLF-YFQOKXJGSA-N |
|---|---|
| SMILES | CCC/C=C/C=C/C(=O)O[C@H]1/C(=C/C(=O)OC)/C[C@H]2C[C@@H](OC(=O)C[C@@H](C[C@@H]3CC(C([C@@](O3)(C[C@@H]4C/C(=C/C(=O)OC)/C[C@@H](O4)/C=C/C([C@@]1(O2)O)(C)C)O)(C)C)OC(=O)C)O)[C@@H](C)O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:25235992 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Candidatus Endobugula sertula NCBITaxon:62101 |
SOURCE_ASSERTION | mibig:BGC0000174 | PMID:15556005 |
Occurrences 0
None cited.
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000174 | Candidatus Endobugula sertula NCBITaxon:62101 |
CLUSTER_UNSTATED | genbank:DQ889941.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000174 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/bryostatin.yaml, which is generated from the committed inventories. Neither is edited by hand.