NaturalProductMech

C-1027

naturalproductmech:mibig-d476afc499 MINTED SEEDED

Structure

Standard InChIKeyDGGZCXUXASNDAC-VXNBTGQKSA-N
SMILESC=c7oc6cc(OC)cc(C(=O)O[C@H]1COC(=O)C[C@H](N)c5cc(O)c(O[C@@H]3C#C/C=C1\C#C/C2=C/C=C\[C@@]23OC4OC(C)(C)C(N(C)C)C(O)C4O)c(Cl)c5)c6[nH]c7=O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. CB02366
NCBITaxon:1703935
SOURCE_ASSERTION mibig:BGC0001584 PMID:27999165

Occurrences 6

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1007/S00253-009-2428-3
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1021/NP0340403
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1021/NP100825Y
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1038/JA.2010.55
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1107/S0907444995004197
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1128/AAC.44.2.382-392.2000

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001584 Streptomyces sp. CB02366
NCBITaxon:1703935
CLUSTER_UNSTATED genbank:KU597647.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001584MIBIG5

This page is generated from data/natural_products/polyketides/c-1027-2.yaml, which is generated from the committed inventories. Neither is edited by hand.