NaturalProductMech

campyrone B

naturalproductmech:mibig-1347378e5d MINTED SEEDED

Structure

Standard InChIKeyPFIUOLPDUMSADF-NSHDSACASA-N
SMILESCC(C)C[C@@H](C1=CC(=CC(=O)O1)OC)NC(=O)C
Stereochemistryfully defined
Cross-referencespubchem:72197063, npatlas:NPA015792

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Aspergillus niger ATCC 1015
NCBITaxon:380704
SOURCE_ASSERTION mibig:BGC0002171 PMID:32159958
Aspergillus niger CBS 101883
NCBITaxon:1450533
SOURCE_ASSERTION mibig:BGC0002275 PMID:32159958

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Aspergillus niger
NCBITaxon:5061
LOTUS DOI:10.1016/J.TET.2013.05.098

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0002171 Aspergillus niger ATCC 1015
NCBITaxon:380704
CLUSTER_UNSTATED genbank:ACJE01000002.1
mibig:BGC0002275 Aspergillus niger CBS 101883
NCBITaxon:1450533
CLUSTER_DEMONSTRATED genbank:KZ821395.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0002171, BGC0002275. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0002171MIBIG2
BGC0002275MIBIG2

This page is generated from data/natural_products/polyketides/campyrone-b.yaml, which is generated from the committed inventories. Neither is edited by hand.