NaturalProductMech

cardol

CHEBI:2120 EXACT SEEDED

Resorcinol substituted at position 5 by a pentadecyl chain.

Structure

Standard InChIKeyKVVSCMOUFCNCGX-UHFFFAOYSA-N
SMILESCCCCCCCCCCCCCCCC1=CC(=CC(=C1)O)O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA008167

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Candidatus Entotheonella sp.
NCBITaxon:2066855
SOURCE_ASSERTION mibig:BGC0002332 DOI:10.1002/cbic.201900352

Occurrences 25

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Ardisia colorata
NCBITaxon:1009002
LOTUS DOI:10.1248/CPB.49.1664
Ardisia colorata
NCBITaxon:1009002
LOTUS DOI:10.1248/CPB.50.1484
Byssomerulius incarnatus
NCBITaxon:1045806
LOTUS DOI:10.1021/NP050520D
Grevillea robusta
NCBITaxon:105748
LOTUS DOI:10.1021/NP0605687
Anacardium occidentale
NCBITaxon:171929
LOTUS DOI:10.1002/PTR.2650070309
Anacardium occidentale
NCBITaxon:171929
LOTUS DOI:10.1016/0031-9422(92)83267-3
Anacardium occidentale
NCBITaxon:171929
LOTUS DOI:10.1021/JF00002A039
Anacardium occidentale
NCBITaxon:171929
LOTUS DOI:10.1021/JF00030A035
Anacardium occidentale
NCBITaxon:171929
LOTUS DOI:10.1021/JF020224W
Anacardium occidentale
NCBITaxon:171929
LOTUS DOI:10.1021/NP50106A021
Anacardium occidentale
NCBITaxon:171929
LOTUS DOI:10.1080/10575639208048898
Streptomyces cyaneus
NCBITaxon:1904
LOTUS DOI:10.1038/JA.2015.22
Streptomyces cyaneus
NCBITaxon:1904
LOTUS DOI:10.7164/ANTIBIOTICS.45.886
Streptomyces cyaneus
NCBITaxon:1904
CHEBI PMID:21462031
Ardisia gigantifolia
NCBITaxon:213405
LOTUS DOI:10.1016/J.PHYTOCHEM.2009.04.004
Baccharis quitensis
NCBITaxon:2707514
LOTUS DOI:10.1016/0031-9422(81)84033-2
Mangifera indica
NCBITaxon:29780
LOTUS DOI:10.1016/0885-5765(87)90041-5
Mangifera indica
NCBITaxon:29780
LOTUS DOI:10.1016/S0031-9422(00)81560-5
Mangifera indica
NCBITaxon:29780
LOTUS DOI:10.1016/S0048-4059(86)80019-4
Ginkgo biloba
NCBITaxon:3311
LOTUS DOI:10.1002/PCA.733
Ginkgo biloba
NCBITaxon:3311
LOTUS DOI:10.1016/J.CHROMA.2009.01.013
Ginkgo biloba
NCBITaxon:3311
LOTUS DOI:10.1515/ZNC-2000-11-1206
Ginkgo biloba
NCBITaxon:3311
CHEBI PMID:21462031
Angelica keiskei
NCBITaxon:357850
LOTUS DOI:10.1016/S0304-3835(03)00466-X
Hakea amplexicaulis
NCBITaxon:3815947
LOTUS DOI:10.1021/TX00004A003

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002332 Candidatus Entotheonella sp.
NCBITaxon:2066855
CLUSTER_DEMONSTRATED genbank:MK988560.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

name-disagreement — ChEBI calls this structure 'cardol' and MIBiG calls it 'Adipostatin A'. They share a Standard InChIKey, so if the names denote different compounds then one upstream record has the wrong structure. Check which.

Provenance

Source conceptSourceVersion
BGC0002332MIBIG2
CHEBI:2120CHEBI3-star

This page is generated from data/natural_products/polyketides/cardol.yaml, which is generated from the committed inventories. Neither is edited by hand.