carotenoid
naturalproductmech:mibig-0f4777d2a4 MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | MYQIMJTUIOIEOX-LVWNLLCFSA-N |
|---|---|
| SMILES | CC[C@@]1(O)CCC2=C(O)C3=C(C(O)=C2[C@H]1O[C@H]1C[C@@H]([C@H](O[C@H]2C[C@H](O)[C@H](O[C@H]4CC[C@H](O)[C@H](C)O4)[C@H](C)O2)[C@H](C)O1)N(C)C)C(=O)C1=C(C(O)=CC=C1)C3=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA013316, pubchem:156935 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, terpene, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces olindensis NCBITaxon:358823 |
SOURCE_ASSERTION | mibig:BGC0000214 | PMID:16810496 |
| Algoriphagus sp. KK10202C NCBITaxon:356796 |
SOURCE_ASSERTION | mibig:BGC0000650 | PMID:16625353 |
Occurrences 8
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1080/00021369.1985.10867016 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1271/BBB1961.49.1207 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1271/BBB1961.49.1951 |
| Streptomyces violaceus NCBITaxon:1936 |
LOTUS | DOI:10.1038/S42003-019-0699-5 |
| Streptomyces violaceus NCBITaxon:1936 |
LOTUS | DOI:10.7164/ANTIBIOTICS.39.430 |
| Algoriphagus NCBITaxon:246875 |
LOTUS | DOI:10.1007/S00438-006-0121-0 |
| Streptomyces olindensis NCBITaxon:358823 |
LOTUS | DOI:10.1021/NP50062A029 |
| Streptomyces olindensis NCBITaxon:358823 |
LOTUS | DOI:10.1038/S42003-019-0699-5 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000214 | Streptomyces olindensis NCBITaxon:358823 |
CLUSTER_UNSTATED | genbank:DQ280500.1 |
| mibig:BGC0000650 | Algoriphagus sp. KK10202C NCBITaxon:356796 |
CLUSTER_UNSTATED | genbank:DQ286432.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
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Open questions 2
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000214, BGC0000650. Confirm they describe the same compound rather than an upstream cross-reference error.
curator-carotenoid-cosmomycin-identity-conflict — How should the cosmomycin B structure be separated from the Algoriphagus carotenoid assertions?
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000214 | MIBIG | 5 |
| BGC0000650 | MIBIG | 3 |
This page is generated from data/natural_products/polyketides/carotenoid.yaml, which is generated from the committed inventories. Neither is edited by hand.