chalcomycin A
naturalproductmech:mibig-5f24f2f1e9 MINTED SEEDED
Structure
| Standard InChIKey | KLGADJPDTCIJLO-JVECKAFRSA-N |
|---|---|
| SMILES | CO[C@@H]1C[C@H](C)O[C@H](OC2C(C)CC(C)(O)C(=O)\C=C\C3OC3C(CO[C@@H]3O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]3OC)C(C)OC(=O)\C=C\C2C)[C@H]1O |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | npatlas:NPA04454 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces bikiniensis NCBITaxon:1896 |
SOURCE_ASSERTION | mibig:BGC0000035 | PMID:15561847 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/JA01067A047 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/NP050358E |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/NP050358E.S001 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000035 | Streptomyces bikiniensis NCBITaxon:1896 |
CLUSTER_UNSTATED | genbank:AY509120.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000035 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/chalcomycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.