chaxamycin A
naturalproductmech:mibig-5f2fad2a0d MINTED SEEDED
Structure
| Standard InChIKey | OWRAZHDHNJAEKU-NMCWGSMOSA-N |
|---|---|
| SMILES | C[C@H]1\C=C\C=C/C(=O)NC2=C(C)C(=O)C3=C(C(O)=C(C)C(O)=C3C2=O)C(=O)\C(C)=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@H](C)[C@H](O)[C@H](C)[C@H]1O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA015733, pubchem:53344650 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces leeuwenhoekii NCBITaxon:1437453 |
SOURCE_ASSERTION | mibig:BGC0001287 | PMID:26092459 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/NP200320U |
| Streptomyces leeuwenhoekii NCBITaxon:1437453 |
LOTUS | DOI:10.1002/BIT.26598 |
| Streptomyces leeuwenhoekii NCBITaxon:1437453 |
LOTUS | DOI:10.1128/AEM.01039-15 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001287 | Streptomyces leeuwenhoekii NCBITaxon:1437453 |
CLUSTER_UNSTATED | genbank:LN831790.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001287 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/chaxamycin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.