NaturalProductMech

chaxamycin B

naturalproductmech:mibig-6c482532dd MINTED SEEDED

Structure

Standard InChIKeyYIELQFCSZNNHLS-AIGVRGBASA-N
SMILESC[C@H]1\C=C\C=C/C(=O)NC2=C(C)C(=O)C3=C(C(O)=C(C)C=C3C2=O)C(=O)\C(C)=C\[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@H](C)[C@H](O)[C@H](C)[C@H]1O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA0253, pubchem:53344651

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces leeuwenhoekii
NCBITaxon:1437453
SOURCE_ASSERTION mibig:BGC0001287 PMID:26092459

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1021/NP200320U

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001287 Streptomyces leeuwenhoekii
NCBITaxon:1437453
CLUSTER_UNSTATED genbank:LN831790.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001287MIBIG5

This page is generated from data/natural_products/polyketides/chaxamycin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.