NaturalProductMech

chlorotonil A

naturalproductmech:mibig-b823ce784d MINTED SEEDED

Structure

Standard InChIKeyRQYZFUUTQJMTMJ-JCSZEPHKSA-N
SMILES[H][C@@]12CC(C)=C[C@@H](C)[C@@]1([H])[C@]1([H])C(=O)C(Cl)(Cl)C(=O)[C@H](C)C(=O)O[C@@H](C)\C=C\C=C/[C@@H](C)[C@]1([H])C=C2
Stereochemistryfully defined
Cross-referencesnpatlas:NPA05497

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Sorangium cellulosum
NCBITaxon:56
SOURCE_ASSERTION mibig:BGC0001299 PMID:26348978

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Sorangium cellulosum
NCBITaxon:56
LOTUS DOI:10.1002/ANGE.200703993
Sorangium cellulosum
NCBITaxon:56
LOTUS DOI:10.1128/AAC.03326-14

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001299 Sorangium cellulosum
NCBITaxon:56
CLUSTER_UNSTATED genbank:KT368180.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001299MIBIG5

This page is generated from data/natural_products/polyketides/chlorotonil-a.yaml, which is generated from the committed inventories. Neither is edited by hand.