chondrochloren A

CHEBI:132426 EXACT SEEDED antimicrobial unspecified

A monocarboxylic acid amide with formula C27H40ClNO7, that is produced by Chondromyces crocatus and exhibits antibiotic properties.

Structure

Standard InChIKey	FYBGSKAWXCBCIQ-JRAUAZSASA-N
SMILES	CCCC[C@@H](C)[C@H](O)[C@H](C)C(=O)C(\C)=C\[C@@H](OC)[C@@H](O)[C@@H](OC)C(=O)N\C=C/C1=CC=C(O)C(Cl)=C1
Stereochemistry	fully defined
Cross-references	npatlas:NPA0508

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Chondromyces crocatus NCBITaxon:52	BGC_CHARACTERIZED	mibig:BGC0000970	PMID:19171307

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Chondromyces crocatus NCBITaxon:52	LOTUS	DOI:10.1002/EJOC.200200699
Chondromyces crocatus NCBITaxon:52	CHEBI	PMID:19171307

Biosynthetic gene clusters 1

Accession	Host	Locus evidence	Genome
mibig:BGC0000970	Chondromyces crocatus NCBITaxon:52	CLUSTER_DEMONSTRATED	genbank:AM988861.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Elsewhere in the fleet

AntibioticMech — CHEBI:132426 (same structure, same inchikey)

Provenance

Source concept	Source	Version
BGC0000970	MIBIG	5
CHEBI:132426	CHEBI	3-star

This page is generated from data/natural_products/polyketides/chondrochloren-a.yaml, which is generated from the committed inventories. Neither is edited by hand.