NaturalProductMech

cinerubin B

naturalproductmech:mibig-80ef61b944 MINTED SEEDED

Structure

Standard InChIKeyZBDDFHXUDIPRSM-DQCCILMQSA-N
SMILES[H][C@]12C[C@H](O[C@@H]3[C@H](C)O[C@H](C[C@@H]3N(C)C)O[C@H]3C[C@](O)(CC)[C@H](C(=O)OC)C4=CC5=C(C(O)=C34)C(=O)C3=C(O)C=CC(O)=C3C5=O)O[C@@H](C)[C@@]1([H])O[C@]1([H])O[C@@H](C)C(=O)C[C@]1([H])O2
Stereochemistryfully defined
Cross-referencesnpatlas:NPA019994

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. SPB074
NCBITaxon:465543
SOURCE_ASSERTION mibig:BGC0000212 PMID:24191063

Occurrences 13

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1002/CBER.19590920820
Streptomyces griseoruber
NCBITaxon:1943
LOTUS DOI:10.1271/BBB.110251
Streptomyces griseoruber
NCBITaxon:1943
LOTUS DOI:10.7164/ANTIBIOTICS.33.49
Streptomyces galilaeus
NCBITaxon:33899
LOTUS DOI:10.7164/ANTIBIOTICS.34.951
Streptomyces eurythermus
NCBITaxon:42237
LOTUS DOI:10.7164/ANTIBIOTICS.45.1599
Streptomyces griseorubiginosus
NCBITaxon:67304
LOTUS DOI:10.1271/BBB.110251
Streptomyces griseorubiginosus
NCBITaxon:67304
LOTUS DOI:10.7164/ANTIBIOTICS.33.49
Streptomyces melanogenes
NCBITaxon:67326
LOTUS DOI:10.1271/BBB.110251
Streptomyces melanogenes
NCBITaxon:67326
LOTUS DOI:10.7164/ANTIBIOTICS.33.49
Streptomyces noboritoensis
NCBITaxon:67337
LOTUS DOI:10.1271/BBB.110251
Streptomyces noboritoensis
NCBITaxon:67337
LOTUS DOI:10.7164/ANTIBIOTICS.33.49
Streptomyces tauricus
NCBITaxon:68274
LOTUS DOI:10.1271/BBB.110251
Streptomyces tauricus
NCBITaxon:68274
LOTUS DOI:10.7164/ANTIBIOTICS.33.49

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000212 Streptomyces sp. SPB074
NCBITaxon:465543
CLUSTER_UNSTATED genbank:GG770539.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000212MIBIG5

This page is generated from data/natural_products/polyketides/cinerubin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.