NaturalProductMech

(+)-citrinin

CHEBI:48712 EXACT SEEDED

Structure

Standard InChIKeyCQIUKKVOEOPUDV-FSPLSTOPSA-N
SMILESC[C@@H]1OC=C2C(O)=C(C(O)=O)C(=O)C(C)=C2[C@H]1C
Stereochemistryfully defined
Cross-referencesnpatlas:NPA014581, pubchem:219203

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, other, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Monascus ruber
NCBITaxon:89489
BGC_CHARACTERIZED mibig:BGC0001338 DOI:10.1039/c5sc04027b
Monascus aurantiacus
NCBITaxon:225353
SOURCE_ASSERTION mibig:BGC0000894 DOI:10.1002/ptr.6830

Occurrences 5

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Guanomyces polythrix
NCBITaxon:110160
LOTUS DOI:10.1016/S0031-9422(01)00278-3
Guanomyces polythrix
NCBITaxon:110160
LOTUS DOI:10.1021/JF030115X
Penicillium citrinum
NCBITaxon:5077
LOTUS DOI:10.1039/P19810002577
Monascus aurantiacus
NCBITaxon:225353
LOTUS DOI:10.1007/S10529-011-0745-Y
Monascus ruber
NCBITaxon:89489
LOTUS DOI:10.1039/C5SC04027B

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0001338 Monascus ruber
NCBITaxon:89489
CLUSTER_DEMONSTRATED genbank:KT781075.1
mibig:BGC0000894 Monascus aurantiacus
NCBITaxon:225353
CLUSTER_UNSTATED genbank:EU309474.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000894, BGC0001338. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0001338MIBIG4
BGC0000894MIBIG4
CHEBI:48712CHEBI3-star

This page is generated from data/natural_products/polyketides/citrinin.yaml, which is generated from the committed inventories. Neither is edited by hand.