NaturalProductMech

colabomycin E

naturalproductmech:mibig-7163dcc196 MINTED SEEDED

Structure

Standard InChIKeyUQUWECQGNYCQSQ-MRNGIOIPSA-N
SMILESO=C(NC1=C[C@](/C=C/C=C/C=C/C=C/C(NC2=C(O)CCC2=O)=O)(O)C3C(O3)C1=O)/C=C/C=C/C=C/C=C\C=C\C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces aureus
NCBITaxon:193461
BGC_CHARACTERIZED mibig:BGC0000213 PMID:24838618

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces aureus
NCBITaxon:193461
LOTUS DOI:10.1002/CBIC.201400068

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000213 Streptomyces aureus
NCBITaxon:193461
CLUSTER_DEMONSTRATED genbank:KF850685.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000213MIBIG4

This page is generated from data/natural_products/polyketides/colabomycin-e.yaml, which is generated from the committed inventories. Neither is edited by hand.