NaturalProductMech

cosmomycin C

naturalproductmech:mibig-12602acb75 MINTED SEEDED

Structure

Standard InChIKeyJRCMJKKALYUURJ-OVYBONNASA-N
SMILESCC[C@@]1(O)C[C@H](O[C@H]2C[C@@H]([C@H](O[C@H]3C[C@H](O)[C@H](O[C@H]4CC[C@H](O)[C@H](C)O4)[C@H](C)O3)[C@H](C)O2)N(C)C)C2=C(O)C3=C(C(O)=C2[C@H]1O[C@H]1C[C@@H]([C@H](O[C@H]2CC[C@H](O[C@H]4CC[C@H](O)[C@H](C)O4)[C@H](C)O2)[C@H](C)O1)N(C)C)C(=O)C1=C(C(O)=CC=C1)C3=O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA02230

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces sp. CNT302
NCBITaxon:1169155
SOURCE_ASSERTION mibig:BGC0001558 PMID:28333450

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1038/S42003-019-0699-5
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1271/BBB1961.49.1951

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001558 Streptomyces sp. CNT302
NCBITaxon:1169155
CLUSTER_UNSTATED genbank:NZ_KB898282.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001558MIBIG5

This page is generated from data/natural_products/polyketides/cosmomycin-c.yaml, which is generated from the committed inventories. Neither is edited by hand.