cosmomycin D
naturalproductmech:mibig-41c6be88f1 MINTED SEEDED
Structure
| Standard InChIKey | DKWBRHNUUTWKAG-JNZMSYBZSA-N |
|---|---|
| SMILES | CC[C@@]1(O)C[C@H](O[C@H]2C[C@@H]([C@H](O[C@H]3C[C@H](O)[C@H](O[C@H]4CC[C@H](O)[C@H](C)O4)[C@H](C)O3)[C@H](C)O2)N(C)C)C2=C(O)C3=C(C(O)=C2[C@H]1O[C@H]1C[C@@H]([C@H](O[C@H]2C[C@H](O)[C@H](O[C@H]4CC[C@H](O)[C@H](C)O4)[C@H](C)O2)[C@H](C)O1)N(C)C)C(=O)C1=C(C(O)=CC=C1)C3=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA01627, pubchem:125715 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is saccharide, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces olindensis NCBITaxon:358823 |
SOURCE_ASSERTION | mibig:BGC0001074 | PMID:24970824 |
Occurrences 9
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1080/00021369.1985.10866713 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1080/00021369.1985.10867016 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1271/BBB1961.49.1951 |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1271/BBB1961.49.259 |
| Streptomyces cyaneus NCBITaxon:1904 |
LOTUS | DOI:10.7164/ANTIBIOTICS.40.116 |
| Streptomyces violaceus NCBITaxon:1936 |
LOTUS | DOI:10.7164/ANTIBIOTICS.44.1110 |
| Streptomyces olindensis NCBITaxon:358823 |
LOTUS | DOI:10.1038/S42003-019-0699-5 |
| Streptomyces olindensis NCBITaxon:358823 |
LOTUS | DOI:10.1128/GENOMEA.00541-14 |
| Streptomyces olindensis NCBITaxon:358823 |
LOTUS | DOI:10.1255/EJMS.948 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001074 | Streptomyces olindensis NCBITaxon:358823 |
CLUSTER_UNSTATED | genbank:JJOH01000002.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001074 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/cosmomycin-d.yaml, which is generated from the committed inventories. Neither is edited by hand.