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cryptosporioptide A

naturalproductmech:mibig-02c505563a MINTED SEEDED

Grounding review: No 3-star ChEBI entry shares this structure, so the record keeps a content-hashed identifier.
What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

Structure

Standard InChIKeyTXRNSKPHZNMMMH-UKYVRAJSSA-N
SMILESC[C@@]12[C@@H](O1)C(=O)C3=C(C4=C(C=CC(=C4O)C5=C(C6=C(C=C5)O[C@]7([C@H]([C@@]8([C@@H](O8)C(=O)C7=C6O)C)OC(=O)CC(=O)O)C)O)O[C@]3([C@H]2OC(=O)CC(=O)O)C)O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA006231

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Cryptosporiopsis sp. 8999
NCBITaxon:2572248		 BGC_CHARACTERIZED mibig:BGC0002063 PMID:30996871

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002063 Cryptosporiopsis sp. 8999
NCBITaxon:2572248 		CLUSTER_DEMONSTRATED genbank:MK182094.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

PRODUCERS & OCCURRENCE 1 producer (1 causal) 0 cited occurrences BIOSYNTHETIC LOCUS 1 gene cluster 0 curated pathway steps NATURAL PRODUCT cryptosporioptide A naturalproductmech:mibig-02c505563a Polyketides TARGETS & BIOACTIVITY 0 molecular targets 0 bioactivities · 0 graphs

Explore across X-Mech

AntibioticMech (cryptosporioptide A) ↗ MediaIngredientMech (naturalproductmech:mibig-02c505563a) ↗ TaxonMech: Cryptosporiopsis sp. 8999 (NCBITaxon:2572248) ↗ PathwayMech (mibig:BGC0002063) ↗

Provenance

Source conceptSourceVersion
BGC0002063MIBIG3

This page is generated from data/natural_products/polyketides/cryptosporioptide-a.yaml, which is generated from the committed inventories. Neither is edited by hand.