curacin A
naturalproductmech:mibig-3d20e0df73 MINTED SEEDED
Structure
| Standard InChIKey | LUEYTMPPCOCKBX-ODRFWBCESA-N |
|---|---|
| SMILES | C[C@H]1CC1C2=N[C@@H](CS2)/C=C\CC/C=C/C=C(\C)/CC[C@H](CC=C)OC |
| Stereochemistry | undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers |
| Cross-references | pubchem:6438908, CHEBI:3961, chembl:CHEMBL89138 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is nrps, pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Lyngbya majuscula NCBITaxon:158786 |
BGC_CORRELATED | mibig:BGC0001165 | PMID:15332855 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Lyngbya majuscula NCBITaxon:158786 |
LOTUS | DOI:10.1021/NP0499261 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001165 | Lyngbya majuscula NCBITaxon:158786 |
CLUSTER_DEMONSTRATED | genbank:AY652953.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001165 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/curacin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.