Cylindrocyclophane D
naturalproductmech:mibig-dbb114994c MINTED SEEDED
What these status tags mean
Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.
Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.
Structure
| Standard InChIKey | ISFVAVZOVOHZSB-IUWWWGALSA-N |
|---|---|
| SMILES | CCCC[C@H]1CCCC[C@@H]([C@H](C2=CC(=C([C@H](CCCC[C@@H]([C@H](C3=CC(=C1C(=C3)O)O)OC(=O)C)C)CCCC)C(=C2)O)O)OC(=O)C)C |
| Stereochemistry | fully defined |
| Cross-references | pubchem:10258912, npatlas:NPA028333, cyanometdb:CyanoMetDB_2365 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 2
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Cylindrospermum licheniforme UTEX B 2014 NCBITaxon:379530 |
BGC_CHARACTERIZED | mibig:BGC0001064 | PMID:23106426 |
| Cylindrospermum licheniforme UTEX B 2014 NCBITaxon:379530 |
SOURCE_ASSERTION | mibig:BGC0001566 | DOI:10.1021/ja308318p |
Occurrences 6
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Nostoc NCBITaxon:1177 |
LOTUS | DOI:10.1021/ACS.JNATPROD.6B01175 |
| Nostoc commune NCBITaxon:1178 |
LOTUS | DOI:10.2172/928495 |
| Cylindrospermum licheniforme NCBITaxon:184932 |
LOTUS | DOI:10.1002/CHIN.199233298 |
| Cylindrospermum licheniforme NCBITaxon:184932 |
LOTUS | DOI:10.1016/S0040-4020(01)87237-9 |
| Cylindrospermum licheniforme NCBITaxon:184932 |
LOTUS | DOI:10.1016/S0040-4020(01)92244-6 |
| Nostoc linckia NCBITaxon:92942 |
LOTUS | DOI:10.2172/928495 |
Biosynthetic gene clusters 2
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001064 | Cylindrospermum licheniforme UTEX B 2014 NCBITaxon:379530 |
CLUSTER_DEMONSTRATED | genbank:JX477167.1 |
| mibig:BGC0001566 | Cylindrospermum licheniforme UTEX B 2014 NCBITaxon:379530 |
CLUSTER_UNSTATED | genbank:KX682397.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Mechanism & Biosynthesis Overview
Explore across X-Mech
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0001064, BGC0001566. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001064 | MIBIG | 5 |
| BGC0001566 | MIBIG | 3 |
This page is generated from data/natural_products/polyketides/cylindrocyclophane-d.yaml, which is generated from the committed inventories. Neither is edited by hand.