dynemicin A
naturalproductmech:mibig-bf5595dbba MINTED SEEDED
Structure
| Standard InChIKey | AFMYMMXSQGUCBK-AKMKHHNQSA-N |
|---|---|
| SMILES | COC1=C([C@H](C)[C@@]23O[C@@]22[C@@H]1C#C\C=C/C#C[C@@H]3NC1=C2C=C(O)C2=C1C(=O)C1=C(C(O)=CC=C1O)C2=O)C(O)=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA0412 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Micromonospora chersina NCBITaxon:47854 |
SOURCE_ASSERTION | mibig:BGC0001060 | PMID:18328078 |
Occurrences 6
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Micromonospora aurantiaca NCBITaxon:47850 |
LOTUS | DOI:10.7164/ANTIBIOTICS.43.1000 |
| Micromonospora globosa NCBITaxon:47863 |
LOTUS | DOI:10.7164/ANTIBIOTICS.43.1000 |
| Micromonospora chersina NCBITaxon:47854 |
LOTUS | DOI:10.1021/JA00037A011 |
| Micromonospora chersina NCBITaxon:47854 |
LOTUS | DOI:10.1111/J.1574-6968.2008.01112.X |
| Micromonospora chersina NCBITaxon:47854 |
LOTUS | DOI:10.7164/ANTIBIOTICS.42.1449 |
| Micromonospora chersina NCBITaxon:47854 |
LOTUS | DOI:10.7164/ANTIBIOTICS.44.1300 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001060 | Micromonospora chersina NCBITaxon:47854 |
CLUSTER_UNSTATED | genbank:EF552206.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001060 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/dynemicin-a.yaml, which is generated from the committed inventories. Neither is edited by hand.