NaturalProductMech

ebelactone A

naturalproductmech:mibig-39007f6149 MINTED SEEDED

Structure

Standard InChIKeyWOISDAHQBUYEAF-QIQXJRRPSA-N
SMILESCC[C@@H](C)[C@H]([C@H](C)C(=O)[C@H](C)/C=C(\C)/C[C@H](C)[C@H]1[C@@H](C(=O)O1)C)O
Stereochemistryfully defined
Cross-referencespubchem:6436820

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Kitasatospora aburaviensis
NCBITaxon:67265
SOURCE_ASSERTION mibig:BGC0000051 PMID:23801186
Kitasatospora aburaviensis
NCBITaxon:67265
SOURCE_ASSERTION mibig:BGC0001580 PMID:27829923

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.7164/ANTIBIOTICS.35.1495

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0000051 Kitasatospora aburaviensis
NCBITaxon:67265
CLUSTER_UNSTATED genbank:KC894072.1
mibig:BGC0001580 Kitasatospora aburaviensis
NCBITaxon:67265
CLUSTER_UNSTATED genbank:LT608336.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000051, BGC0001580. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0000051MIBIG5
BGC0001580MIBIG3

This page is generated from data/natural_products/polyketides/ebelactone-a.yaml, which is generated from the committed inventories. Neither is edited by hand.