ebelactone B
naturalproductmech:mibig-8ffa6e142d MINTED SEEDED enzyme inhibitor
Structure
| Standard InChIKey | UNBMQQNYLCPCHS-VYNDPHDASA-N |
|---|---|
| SMILES | CC[C@H]1[C@@H](OC1=O)[C@@H](C)C/C(=C/[C@@H](C)C(=O)[C@@H](C)[C@@H]([C@H](C)CC)O)/C |
| Stereochemistry | fully defined |
| Cross-references | pubchem:6436821 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Kitasatospora aburaviensis NCBITaxon:67265 |
SOURCE_ASSERTION | mibig:BGC0000051 | PMID:23801186 |
Occurrences 1
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.7164/ANTIBIOTICS.35.1495 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000051 | Kitasatospora aburaviensis NCBITaxon:67265 |
CLUSTER_UNSTATED | genbank:KC894072.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Bioactivities 1
| Assay | Result | Reference |
|---|---|---|
| qHTS for Inhibitors of Polymerase Kappa | 33.5875 uM | pubchem.aid:588579 |
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000051 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/ebelactone-b.yaml, which is generated from the committed inventories. Neither is edited by hand.