endocrocin

CHEBI:64450 EXACT SEEDED

What these status tags mean

Curation status describes a workflow state. SEEDED means the record entered through the source-seeding workflow; it does not imply that no later curation occurred. PROPOSED marks an addition awaiting review; REVIEWED records curator sign-off on identity, structure, filing class and producer claims; DEPRECATED retains a superseded or out-of-scope record. These are workflow decisions, not independently verified human review. Agent-assisted contributions may appear in the record history.

Grounding describes the identifier mapping: EXACT uses an ontology identity asserted by the source; MINTED keeps a local identifier when no defensible ontology identity is available; REVIEW_NEEDED flags an exact structure whose ontology identity needs adjudication. The grounding note retains any unresolved alternatives. These tags do not establish the strength of producer or activity evidence.

A trihydroxyanthraquinone that is 9,10-anthraquinone which is substituted by a carboxy group at position 2, a methyl group at position 3, and hydroxy groups at positions 1, 6, and 8.

Structure

Standard InChIKey	UZOHDKGTYVTYDZ-UHFFFAOYSA-N
SMILES	CC1=C(C(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)O)O)O)C(=O)O
Stereochemistry	fully defined
Cross-references	pubchem:160483

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

Taxon	Basis	Cluster	Evidence
Aspergillus fumigatus Af293 NCBITaxon:330879	BGC_CHARACTERIZED	mibig:BGC0001118	PMID:22492455
Claviceps purpurea 20.1 NCBITaxon:1111077	SOURCE_ASSERTION	mibig:BGC0001886	DOI:10.1186/s40694-016-0020-z

Occurrences 12

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

Taxon	Source	Reference
Rumex nepalensis NCBITaxon:174652	LOTUS	DOI:10.1055/S-0030-1249779
Cetraria ornata NCBITaxon:180485	LOTUS	DOI:10.1248/CPB.20.1082
Cortinarius cardinalis NCBITaxon:183877	LOTUS	DOI:10.1071/C97154
Talaromyces islandicus NCBITaxon:28573	LOTUS	DOI:10.3891/ACTA.CHEM.SCAND.13-0386
Cortinarius sanguineus NCBITaxon:304759	LOTUS	DOI:10.1515/ZNC-2000-3-410
Cortinarius cinnabarinus NCBITaxon:304808	LOTUS	DOI:10.1002/CBER.19721050915
Planococcus kraunhiae NCBITaxon:494597	LOTUS	DOI:10.1271/BBB.100742
Aspergillus amstelodami NCBITaxon:5054	LOTUS	DOI:10.1248/CPB1953.1.160
Claviceps purpurea NCBITaxon:5111	LOTUS	DOI:10.1055/S-0028-1100024
Penicillium oxalicum NCBITaxon:69781	LOTUS	DOI:10.1007/S10600-010-9572-Y
Aspergillus fumigatus NCBITaxon:746128	LOTUS	DOI:10.1128/AEM.07710-11
Setophoma terrestris NCBITaxon:798162	LOTUS	DOI:10.7164/ANTIBIOTICS.32.1256

Biosynthetic gene clusters 2

Accession	Host	Locus evidence	Genome
mibig:BGC0001118	Aspergillus fumigatus Af293 NCBITaxon:330879	CLUSTER_DEMONSTRATED	genbank:CM000172.1
mibig:BGC0001886	Claviceps purpurea 20.1 NCBITaxon:1111077	CLUSTER_UNSTATED	genbank:CAGA01000032.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Mechanism & Biosynthesis Overview

Causal graph — biosynthesis 6 nodes, 5 edges

Database-annotated endocrocin genetic associations with sequence-verified Af293 EncA/B/C/D reference proteins. UniProt reports loss after encA/B/C disruption and increased production after encD disruption. These are selected native references, not verified experimental alleles. Primary methods and the experimental-strain mapping remain unresolved; effects are not universal requirements across conditions or alternative pathways. No complete reaction sequence, direct regulation, protein complex, bioactivity target or source-grade upgrade is asserted.

Subject	Predicate	Object	Notes	Evidence
EncA (Af293 reference)	has_database_annotated_deletion_associated_loss_of	Endocrocin production in the database-reported genetic context	The node is a selected native Af293 protein reference for the named gene. The edge is a database-reported genetic phenotype, not the direct molecular action of the canonical protein or proof that the experimental allele is identical to Af293.	https://www.uniprot.org/uniprotkb/Q4W944/entry https://www.ncbi.nlm.nih.gov/protein/EAL84397.1 https://www.ncbi.nlm.nih.gov/nuccore/CM000172.1 reference https://www.uniprot.org/uniprotkb/Q4W944/entry evidence type DATABASE_ASSERTION retrieved on 2026-10-11 snippet Abolishes the production of endocrocin notes Reviewed UniProtKB/Swiss-Prot disruption-phenotype annotation, entry version 121, sequence version 1, gene encA, AFUA_4G00210, 1775 aa, NCBITaxon:330879. The disruption annotation cites PMID22492455 and PMID23592999. The exact stoichiometric catalytic annotation instead carries ECO:0000305. Neither that reaction, a purified-protein assay nor the separate virulence annotation is asserted here. Primary methods, exact experimental strain and complete allele were not independently inspected. The reported effect is not generalized to every strain, culture condition or alternative endocrocin route. Protein-existence annotation remains 1: Evidence at protein level; sequence agreement is not a new experimental demonstration. reference https://www.ncbi.nlm.nih.gov/protein/EAL84397.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes Native Af293 reference AFUA_4G00210, 1775 aa, EAL84397.1: join(AAHF01000017.1:384731..385044, AAHF01000017.1:385106..385406, AAHF01000017.1:385458..388895, AAHF01000017.1:388954..390228). Complete CDS translation with 4 spliced exons, deposited translation, separately retrieved GenPept and reviewed UniProt sequences match exactly. Gene/locus and explicit UniProt nucleotide/protein cross-references also agree. This establishes reference identity, not the sequence of a tested deletion strain or an engineered construct. reference https://www.ncbi.nlm.nih.gov/nuccore/CM000172.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes The native contig interval AAHF01000017.1:380991..390228 is the exact reverse complement of chromosome 4 CM000172.1:55988..65225 within the source-listed BGC0001118 interval 54334..75724. This protein's chromosome exons, in translation order with 1-based inclusive coordinates, are 61172..61485 (-), 60810..61110 (-), 57321..60758 (-), 55988..57262 (-). Spliced chromosome translation also matches the deposited, GenPept and UniProt sequences. Genomic location and sequence consistency do not independently demonstrate production by this strain or revalidate the imported BGC_CHARACTERIZED grade.
EncB (Af293 reference)	has_database_annotated_deletion_associated_loss_of	Endocrocin production in the database-reported genetic context	The node is a selected native Af293 protein reference for the named gene. The edge is a database-reported genetic phenotype, not the direct molecular action of the canonical protein or proof that the experimental allele is identical to Af293.	https://www.uniprot.org/uniprotkb/Q4W945/entry https://www.ncbi.nlm.nih.gov/protein/EAL84396.1 https://www.ncbi.nlm.nih.gov/nuccore/CM000172.1 reference https://www.uniprot.org/uniprotkb/Q4W945/entry evidence type DATABASE_ASSERTION retrieved on 2026-10-11 snippet Abolishes the production of endocrocin notes Reviewed UniProtKB/Swiss-Prot disruption-phenotype annotation, entry version 91, sequence version 1, gene encB, AFUA_4G00220, 315 aa, NCBITaxon:330879. The disruption annotation cites PMID22492455. Its specific Rhea reaction is transferred by similarity, ECO:0000250 from Q0CCY4; it is not independently demonstrated native EncB chemistry in this graph. Primary methods, exact experimental strain and complete allele were not independently inspected. The reported effect is not generalized to every strain, culture condition or alternative endocrocin route. Protein-existence annotation remains 1: Evidence at protein level; sequence agreement is not a new experimental demonstration. reference https://www.ncbi.nlm.nih.gov/protein/EAL84396.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes Native Af293 reference AFUA_4G00220, 315 aa, EAL84396.1: join(AAHF01000017.1:383360..383491, AAHF01000017.1:383551..384366). Complete CDS translation with 2 spliced exons, deposited translation, separately retrieved GenPept and reviewed UniProt sequences match exactly. Gene/locus and explicit UniProt nucleotide/protein cross-references also agree. This establishes reference identity, not the sequence of a tested deletion strain or an engineered construct. reference https://www.ncbi.nlm.nih.gov/nuccore/CM000172.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes The native contig interval AAHF01000017.1:380991..390228 is the exact reverse complement of chromosome 4 CM000172.1:55988..65225 within the source-listed BGC0001118 interval 54334..75724. This protein's chromosome exons, in translation order with 1-based inclusive coordinates, are 62725..62856 (-), 61850..62665 (-). Spliced chromosome translation also matches the deposited, GenPept and UniProt sequences. Genomic location and sequence consistency do not independently demonstrate production by this strain or revalidate the imported BGC_CHARACTERIZED grade.
EncC (Af293 reference)	has_database_annotated_deletion_associated_loss_of	Endocrocin production in the database-reported genetic context	The node is a selected native Af293 protein reference for the named gene. The edge is a database-reported genetic phenotype, not the direct molecular action of the canonical protein or proof that the experimental allele is identical to Af293.	https://www.uniprot.org/uniprotkb/A4DA85/entry https://www.ncbi.nlm.nih.gov/protein/EBA27176.1 https://www.ncbi.nlm.nih.gov/nuccore/CM000172.1 reference https://www.uniprot.org/uniprotkb/A4DA85/entry evidence type DATABASE_ASSERTION retrieved on 2026-10-11 snippet abolishes the production of endocrocin notes Reviewed UniProtKB/Swiss-Prot disruption-phenotype annotation, entry version 63, sequence version 1, gene encC, AFUA_4G00225, 181 aa, NCBITaxon:330879. The disruption annotation cites PMID22492455 and also mentions unstable anthrone production. No exact anthrone structure, final reaction, spontaneous oxidation rate or substrate-product step is assigned here. Primary methods, exact experimental strain and complete allele were not independently inspected. The reported effect is not generalized to every strain, culture condition or alternative endocrocin route. Protein-existence annotation remains 1: Evidence at protein level; sequence agreement is not a new experimental demonstration. reference https://www.ncbi.nlm.nih.gov/protein/EBA27176.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes Native Af293 reference AFUA_4G00225, 181 aa, EBA27176.1: complement(join(AAHF01000017.1:382421..382905, AAHF01000017.1:382987..383047)). Complete CDS translation with 2 spliced exons, deposited translation, separately retrieved GenPept and reviewed UniProt sequences match exactly. Gene/locus and explicit UniProt nucleotide/protein cross-references also agree. This establishes reference identity, not the sequence of a tested deletion strain or an engineered construct. reference https://www.ncbi.nlm.nih.gov/nuccore/CM000172.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes The native contig interval AAHF01000017.1:380991..390228 is the exact reverse complement of chromosome 4 CM000172.1:55988..65225 within the source-listed BGC0001118 interval 54334..75724. This protein's chromosome exons, in translation order with 1-based inclusive coordinates, are 63169..63229 (+), 63311..63795 (+). Spliced chromosome translation also matches the deposited, GenPept and UniProt sequences. Genomic location and sequence consistency do not independently demonstrate production by this strain or revalidate the imported BGC_CHARACTERIZED grade.
EncD (Af293 reference)	has_database_annotated_deletion_associated_increase_in	Endocrocin production in the database-reported genetic context	The node is a selected native Af293 protein reference for the named gene. The edge is a database-reported genetic phenotype, not the direct molecular action of the canonical protein or proof that the experimental allele is identical to Af293.	https://www.uniprot.org/uniprotkb/Q4W946/entry https://www.ncbi.nlm.nih.gov/protein/EAL84395.2 https://www.ncbi.nlm.nih.gov/nuccore/CM000172.1 reference https://www.uniprot.org/uniprotkb/Q4W946/entry evidence type DATABASE_ASSERTION retrieved on 2026-10-11 snippet Results in increased endocrocin production notes Reviewed UniProtKB/Swiss-Prot disruption-phenotype annotation, entry version 101, sequence version 2, gene encD, AFUA_4G00230, 337 aa, NCBITaxon:330879. The disruption annotation cites PMID22492455 and has the opposite production direction to the other three deletions. Increased product after deletion does not establish direct transcriptional repression, a specific endocrocin-modifying reaction or a quantified fold change. The database leaves the exact function unresolved. Primary methods, exact experimental strain and complete allele were not independently inspected. The reported effect is not generalized to every strain, culture condition or alternative endocrocin route. Protein-existence annotation remains 1: Evidence at protein level; sequence agreement is not a new experimental demonstration. reference https://www.ncbi.nlm.nih.gov/protein/EAL84395.2 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes Native Af293 reference AFUA_4G00230, 337 aa, EAL84395.2: join(AAHF01000017.1:380991..381216, AAHF01000017.1:381265..381740, AAHF01000017.1:381804..382115). Complete CDS translation with 3 spliced exons, deposited translation, separately retrieved GenPept and reviewed UniProt sequences match exactly. Gene/locus and explicit UniProt nucleotide/protein cross-references also agree. This establishes reference identity, not the sequence of a tested deletion strain or an engineered construct. reference https://www.ncbi.nlm.nih.gov/nuccore/CM000172.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes The native contig interval AAHF01000017.1:380991..390228 is the exact reverse complement of chromosome 4 CM000172.1:55988..65225 within the source-listed BGC0001118 interval 54334..75724. This protein's chromosome exons, in translation order with 1-based inclusive coordinates, are 65000..65225 (-), 64476..64951 (-), 64101..64412 (-). Spliced chromosome translation also matches the deposited, GenPept and UniProt sequences. Genomic location and sequence consistency do not independently demonstrate production by this strain or revalidate the imported BGC_CHARACTERIZED grade.
Endocrocin production in the database-reported genetic context	produces	Endocrocin		https://www.uniprot.org/uniprotkb/Q4W944/entry reference https://www.uniprot.org/uniprotkb/Q4W944/entry evidence type DATABASE_ASSERTION retrieved on 2026-10-11 notes The reviewed function annotation identifies the enc cluster with endocrocin biosynthesis. This names the compound output of the database-described process, not a final EncD-catalyzed reaction, a complete reconstitution, or production in every mutant. The stored endocrocin structure agrees with PubChem CID 160483 and an independent RDKit representation check. Atrochrysone derivatives, anthrones and trypacidin are not equated with this exact owner.

Every edge carries its own citation; an uncited edge is refused by the corpus tests.

Causal graph — biosynthesis 6 nodes, 5 edges

Database-annotated endocrocin associations with sequence-verified native Af293 LaeA, CsdA and LaeB references, not verified experimental alleles. LaeA deletion is reported to reduce production. CsdA and LaeB have unsigned regulatory associations only; fumiquinazoline C phenotypes and similarity-derived splicing details are not transferred to endocrocin. Separate process nodes preserve distinct source contexts. No direct binding, complex stoichiometry, exact catalytic step, universal essentiality, virulence mechanism or producer-grade upgrade is asserted.

Subject	Predicate	Object	Notes	Evidence
LaeA (Af293 reference)	has_database_annotated_deletion_associated_reduction_in	Endocrocin production in the database-reported LaeA context	Selected native Af293 reference, not a verified experimental allele. The predicate records the scope of the database annotation, not a demonstrated direct molecular action.	https://www.uniprot.org/uniprotkb/Q4WRY5/entry https://www.ncbi.nlm.nih.gov/protein/EAL90797.1 https://www.ncbi.nlm.nih.gov/nuccore/AAHF01000004.1 reference https://www.uniprot.org/uniprotkb/Q4WRY5/entry evidence type DATABASE_ASSERTION retrieved on 2026-10-11 snippet Reduces the production of endocrocin notes Reviewed UniProtKB disruption phenotype annotation; entry version 97, sequence version 1; laeA, AFUA_1G14660, 373 aa, NCBITaxon:330879. The disruption annotation cites PMID:22492455, DOI:10.1128/AEM.07710-11. Reduction is not complete loss or universal essentiality. The LaeA automethylation and velvet-complex annotations are similarity-derived and are not adopted as direct endocrocin mechanisms. Canonical EAL90797.1 is selected; AAR01218.1 is ALT_SEQ with an erroneous-gene-model warning. The alternate sequence was not retrieved or compared, so no measured sequence difference is asserted. Primary methods, strain/construct identity, assay conditions and exact endocrocin-specific intermediate mechanism were not independently established. Protein-existence annotation remains 2: Evidence at transcript level. reference https://www.ncbi.nlm.nih.gov/protein/EAL90797.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes Native Af293 AFUA_1G14660, EAL90797.1, 373 aa. Complete spliced CDS translation, deposited translation, separately retrieved GenPept and reviewed UniProt sequences match exactly. Explicit nucleotide/protein cross-references and locus agree. This establishes reference identity, not the sequence of an assayed mutant or an independent experiment demonstrating regulation. reference https://www.ncbi.nlm.nih.gov/nuccore/AAHF01000004.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes Native CDS: join(AAHF01000004.1:1670850..1671079, AAHF01000004.1:1671225..1672116). Exact exon coordinates and strand, codon start 1, translation table 1, complete start/stop and unambiguous sequence were checked. This is a global-regulator reference outside the Enc cluster, not an additional BGC0001118 biosynthetic gene or a new producer-grade assertion.
CsdA (Af293 reference)	has_database_annotated_regulatory_association_with	Endocrocin production in the database-reported CsdA/LaeB context	Selected native Af293 reference, not a verified experimental allele. The predicate records the scope of the database annotation, not a demonstrated direct molecular action.	https://www.uniprot.org/uniprotkb/Q4WE89/entry https://www.ncbi.nlm.nih.gov/protein/EAL86088.1 https://www.ncbi.nlm.nih.gov/nuccore/AAHF01000011.1 reference https://www.uniprot.org/uniprotkb/Q4WE89/entry evidence type DATABASE_ASSERTION retrieved on 2026-10-11 snippet including gliotoxin, endocrocin, fumihopaside and neosartoricin notes Reviewed UniProtKB function annotation; entry version 129, sequence version 1; csdA, AFUA_5G02160, 613 aa, NCBITaxon:330879. The function annotation explicitly includes endocrocin among regulated products and cites PMID:41498629, DOI:10.1002/advs.202519021. This is unsigned regulation: no endocrocin-specific increase, decrease, deletion phenotype or fold change is assigned. The quantified disruption phenotypes and SebA/fmqA-E mechanism concern fumiquinazoline C, not endocrocin. Motif-specific GUCGGUAU and intron-2 splicing details transferred by similarity are not adopted as native endocrocin mechanisms. No physical-complex or direct promoter-binding edge is asserted. Primary methods, strain/construct identity, assay conditions and exact endocrocin-specific intermediate mechanism were not independently established. Protein-existence annotation remains 1: Evidence at protein level. reference https://www.ncbi.nlm.nih.gov/protein/EAL86088.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes Native Af293 AFUA_5G02160, EAL86088.1, 613 aa. Complete spliced CDS translation, deposited translation, separately retrieved GenPept and reviewed UniProt sequences match exactly. Explicit nucleotide/protein cross-references and locus agree. This establishes reference identity, not the sequence of an assayed mutant or an independent experiment demonstrating regulation. reference https://www.ncbi.nlm.nih.gov/nuccore/AAHF01000011.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes Native CDS: join(AAHF01000011.1:651949..652104, AAHF01000011.1:652255..652312, AAHF01000011.1:652476..653182, AAHF01000011.1:653244..654164). Exact exon coordinates and strand, codon start 1, translation table 1, complete start/stop and unambiguous sequence were checked. This is a global-regulator reference outside the Enc cluster, not an additional BGC0001118 biosynthetic gene or a new producer-grade assertion.
LaeB (Af293 reference)	has_database_annotated_regulatory_association_with	Endocrocin production in the database-reported CsdA/LaeB context	Selected native Af293 reference, not a verified experimental allele. The predicate records the scope of the database annotation, not a demonstrated direct molecular action.	https://www.uniprot.org/uniprotkb/Q4WUK4/entry https://www.ncbi.nlm.nih.gov/protein/EAL91722.1 https://www.ncbi.nlm.nih.gov/nuccore/AAHF01000003.1 reference https://www.uniprot.org/uniprotkb/Q4WUK4/entry evidence type DATABASE_ASSERTION retrieved on 2026-10-11 snippet including gliotoxin, endocrocin, fumihopaside and neosartoricin notes Reviewed UniProtKB function annotation; entry version 68, sequence version 1; laeB, AFUA_5G08770, 609 aa, NCBITaxon:330879. The function annotation explicitly includes endocrocin among regulated products and cites PMID:41498629, DOI:10.1002/advs.202519021. This is unsigned regulation: no endocrocin-specific increase, decrease, deletion phenotype or fold change is assigned. The quantified disruption phenotypes and SebA/fmqA-E mechanism concern fumiquinazoline C, not endocrocin. Motif-specific GUCGGUAU and intron-2 splicing details transferred by similarity are not adopted as native endocrocin mechanisms. No physical-complex or direct promoter-binding edge is asserted. Primary methods, strain/construct identity, assay conditions and exact endocrocin-specific intermediate mechanism were not independently established. Protein-existence annotation remains 1: Evidence at protein level. reference https://www.ncbi.nlm.nih.gov/protein/EAL91722.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes Native Af293 AFUA_5G08770, EAL91722.1, 609 aa. Complete spliced CDS translation, deposited translation, separately retrieved GenPept and reviewed UniProt sequences match exactly. Explicit nucleotide/protein cross-references and locus agree. This establishes reference identity, not the sequence of an assayed mutant or an independent experiment demonstrating regulation. reference https://www.ncbi.nlm.nih.gov/nuccore/AAHF01000003.1 evidence type CURATOR_INFERENCE retrieved on 2026-10-11 notes Native CDS: complement(join(AAHF01000003.1:1699640..1700424 ,AAHF01000003.1:1700838..1701882)). Exact exon coordinates and strand, codon start 1, translation table 1, complete start/stop and unambiguous sequence were checked. This is a global-regulator reference outside the Enc cluster, not an additional BGC0001118 biosynthetic gene or a new producer-grade assertion.
Endocrocin production in the database-reported LaeA context	produces	Endocrocin		https://www.uniprot.org/uniprotkb/Q4WRY5/entry reference https://www.uniprot.org/uniprotkb/Q4WRY5/entry evidence type DATABASE_ASSERTION retrieved on 2026-10-11 notes The function annotation names endocrocin as a regulated product. This edge identifies the product of the cited regulatory context; it is not a terminal catalytic reaction or proof of production in every mutant, strain or condition. The two source contexts are not equated. The owner structure is unchanged from the PubChem CID160483/RDKit identity audit.
Endocrocin production in the database-reported CsdA/LaeB context	produces	Endocrocin		https://www.uniprot.org/uniprotkb/Q4WUK4/entry reference https://www.uniprot.org/uniprotkb/Q4WUK4/entry evidence type DATABASE_ASSERTION retrieved on 2026-10-11 notes The function annotation names endocrocin as a regulated product. This edge identifies the product of the cited regulatory context; it is not a terminal catalytic reaction or proof of production in every mutant, strain or condition. The two source contexts are not equated. The owner structure is unchanged from the PubChem CID160483/RDKit identity audit.

Every edge carries its own citation; an uncited edge is refused by the corpus tests.

Explore across X-Mech

AntibioticMech (endocrocin) ↗ MediaIngredientMech (CHEBI:64450) ↗ TaxonMech: Aspergillus fumigatus Af293 (NCBITaxon:330879) ↗ TaxonMech: Claviceps purpurea 20.1 (NCBITaxon:1111077) ↗ PathwayMech (mibig:BGC0001118) ↗ PathwayMech (mibig:BGC0001886) ↗

Open questions 3

shared-structure — This structure is reported by more than one MIBiG entry: BGC0001118, BGC0001886. Confirm they describe the same compound rather than an upstream cross-reference error.

curator-endocrocin-enc-reference-and-experimental-limits — Which experimental strains and native reactions support the Enc associations and the imported Af293 producer grade?

curator-endocrocin-global-regulator-limits — Which experimental alleles, conditions and endocrocin-specific effects support the global-regulator annotations?

Provenance

Source concept	Source	Version
BGC0001118	MIBIG	5
BGC0001886	MIBIG	2
CHEBI:64450	CHEBI	3-star

This page is generated from data/natural_products/polyketides/endocrocin.yaml, which is generated from the committed inventories. Neither is edited by hand.