NaturalProductMech

epemicin B

naturalproductmech:mibig-30cb089bda MINTED SEEDED

Structure

Standard InChIKeyVNZWETIARFTEAV-GZNXHPRQSA-N
SMILESCC[C@H](O[C@H]1C[C@](C)(N)[C@H](O)[C@H](C)O1)[C@H](C)[C@H](O)[C@H](C=C[C@@H]1CC=C(C)[C@@H](O)[C@@H](C)[C@H](O)C[C@@H](O)[C@@H](C)[C@H](O)C[C@@H]2C[C@H](O)[C@@H](O)[C@](O)(C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](O[C@H]4C[C@@H](N)[C@H](O)[C@@H](C)O4)[C@H]3O[C@@H]3O[C@H](C)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](C)C=C[C@@H](O)C[C@@H](O)[C@@H](C)C=CC(=O)O1)O2)CC
Stereochemistryfully defined
Cross-referencesnpatlas:NPA033171

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Kutzneria sp. CA-103260
NCBITaxon:2802641
BGC_CHARACTERIZED mibig:BGC0002349 PMID:34279911

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Kutzneria
NCBITaxon:43356
LOTUS DOI:10.1021/ACSCHEMBIO.1C00318

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002349 Kutzneria sp. CA-103260
NCBITaxon:2802641
CLUSTER_DEMONSTRATED genbank:CP073318.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002349MIBIG3

This page is generated from data/natural_products/polyketides/epemicin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.