fluostatin C
naturalproductmech:mibig-56bc8e5dd3 MINTED SEEDED
Structure
| Standard InChIKey | CXDDSWUAYSPFRJ-BPQIPLTHSA-N |
|---|---|
| SMILES | C[C@@]12[C@@H](O1)[C@@H](C3=C4C(=C(C=C3C2=O)O)C5=C(C4=O)C=CC=C5O)O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA010700 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Micromonospora rosaria NCBITaxon:47874 |
SOURCE_ASSERTION | mibig:BGC0001904 | DOI:10.1021/acs.orglett.5b02683 |
Occurrences 4
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1038/JA.2006.15 |
| Streptomyces albidoflavus NCBITaxon:1886 |
LOTUS | DOI:10.1038/JA.2006.41 |
| Streptomyces coelicolor NCBITaxon:1902 |
LOTUS | DOI:10.1038/JA.2006.41 |
| Micromonospora rosaria NCBITaxon:47874 |
LOTUS | DOI:10.1021/NP300505Y |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001904 | Micromonospora rosaria NCBITaxon:47874 |
CLUSTER_UNSTATED | genbank:KT726162.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001904 | MIBIG | 2 |
This page is generated from data/natural_products/polyketides/fluostatin-c.yaml, which is generated from the committed inventories. Neither is edited by hand.