NaturalProductMech

fluostatin F

naturalproductmech:mibig-5099894cd7 MINTED SEEDED

Structure

Standard InChIKeyCDBWDMSUWPFBMG-NZSAHSFTSA-N
SMILES[H][C@@]12O[C@]1(C)C(=O)C1=CC(O)=C3C4=C(C=CC=C4O)C(=O)C3=C1[C@H]2OC
Stereochemistryfully defined
Cross-referencesnpatlas:NPA05841, pubchem:71460594

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
uncultured bacterium BAC AB649/1850
NCBITaxon:1037453
SOURCE_ASSERTION mibig:BGC0000223 PMID:20690632

Occurrences 1

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Micromonospora rosaria
NCBITaxon:47874
LOTUS DOI:10.1021/NP300505Y

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000223 uncultured bacterium BAC AB649/1850
NCBITaxon:1037453
CLUSTER_DEMONSTRATED genbank:HM193369.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000223MIBIG5

This page is generated from data/natural_products/polyketides/fluostatin-f.yaml, which is generated from the committed inventories. Neither is edited by hand.