NaturalProductMech

fluostatin G/H

naturalproductmech:mibig-d6c7fe6812 MINTED SEEDED

Structure

Standard InChIKeyUECRBQDJIASDQW-XCKPJGFKSA-N
SMILESCCCC(C)C(=O)O[C@@H]1[C@@H]2[C@@](O2)(C(=O)C3=CC(=C4C5=C(C=CC=C5O)C(=O)C4=C13)O)C
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA020332

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Micromonospora rosaria
NCBITaxon:47874
SOURCE_ASSERTION mibig:BGC0001904 DOI:10.1021/acs.orglett.5b02683

Occurrences 0

None cited.

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001904 Micromonospora rosaria
NCBITaxon:47874
CLUSTER_UNSTATED genbank:KT726162.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001904MIBIG2

This page is generated from data/natural_products/polyketides/fluostatin-g-h.yaml, which is generated from the committed inventories. Neither is edited by hand.