NaturalProductMech

fogacin

naturalproductmech:mibig-b99eff59ad MINTED SEEDED

Structure

Standard InChIKeyWGMNUJNCGZFZPD-GZALTDKGSA-N
SMILESC[C@H]1C2=C(C3=C(C=C2C[C@@H](O1)CC(=O)O)C(CCC3=O)O)O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencespubchem:11493248

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Actinoplanes missouriensis 431
NCBITaxon:512565
SOURCE_ASSERTION mibig:BGC0002021 PMID:30556239

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Actinoplanes missouriensis
NCBITaxon:1866
LOTUS DOI:10.1002/CBIC.201800640
Streptomyces
NCBITaxon:1883
LOTUS DOI:10.1038/JA.2006.45

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0002021 Actinoplanes missouriensis 431
NCBITaxon:512565
CLUSTER_UNSTATED genbank:AP012319.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0002021MIBIG3

This page is generated from data/natural_products/polyketides/fogacin-2.yaml, which is generated from the committed inventories. Neither is edited by hand.