formicamycin B
naturalproductmech:mibig-b7882f52a2 MINTED SEEDED antibacterial
Structure
| Standard InChIKey | DZLMIXIOUIFBDM-ACSYHNTCSA-N |
|---|---|
| SMILES | CC1=C(C(=CC(=C1Cl)OC)O)C2=CC(=C(C3=C2C(=O)[C@@]4([C@H](C3)C(C5=C(C4=O)C(=CC(=C5)O)O)(C)C)O)Cl)OC |
| Stereochemistry | fully defined |
| Cross-references | pubchem:146684582 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces sp. KY5 NCBITaxon:1958824 |
SOURCE_ASSERTION | mibig:BGC0001590 | DOI:10.1016/j.chembiol.2020.12.011 |
Occurrences 2
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces formicae NCBITaxon:1616117 |
LOTUS | DOI:10.1039/C6SC04265A |
| Streptomyces NCBITaxon:1883 |
LOTUS | DOI:10.1021/ACS.JNATPROD.0C00161 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0001590 | Streptomyces sp. KY5 NCBITaxon:1958824 |
CLUSTER_UNSTATED | genbank:KX859301.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — antibioticmech:aro-39c9b140ad (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0001590 | MIBIG | 5 |
This page is generated from data/natural_products/polyketides/formicamycin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.