frenolicin B
CHEBI:48201 EXACT SEEDED antimicrobial unspecified
Structure
| Standard InChIKey | AVCPRTNVVRPELB-YRUZYCQGSA-N |
|---|---|
| SMILES | [H][C@@]12CC(=O)O[C@]1([H])C1=C([C@@H](CCC)O2)C(=O)C2=C(O)C=CC=C2C1=O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA015910 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 1
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Streptomyces roseofulvus NCBITaxon:33902 |
SOURCE_ASSERTION | mibig:BGC0000225 | PMID:8181754 |
Occurrences 6
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Streptomyces fradiae NCBITaxon:1906 |
LOTUS | DOI:10.1021/NP400231R |
| Streptomyces fradiae NCBITaxon:1906 |
LOTUS | DOI:10.7164/ANTIBIOTICS.31.959 |
| Streptomyces roseofulvus NCBITaxon:33902 |
LOTUS | DOI:10.1016/0378-1119(94)90351-4 |
| Streptomyces roseofulvus NCBITaxon:33902 |
LOTUS | DOI:10.1021/NP400231R |
| Streptomyces roseofulvus NCBITaxon:33902 |
LOTUS | DOI:10.7164/ANTIBIOTICS.31.959 |
| Streptomyces roseofulvus NCBITaxon:33902 |
LOTUS | DOI:10.7164/ANTIBIOTICS.39.1343 |
Biosynthetic gene clusters 1
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0000225 | Streptomyces roseofulvus NCBITaxon:33902 |
CLUSTER_UNSTATED | genbank:AF058302.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Elsewhere in the fleet
- AntibioticMech — CHEBI:48201 (same structure, same inchikey)
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0000225 | MIBIG | 5 |
| CHEBI:48201 | CHEBI | 3-star |
This page is generated from data/natural_products/polyketides/frenolicin-b.yaml, which is generated from the committed inventories. Neither is edited by hand.