NaturalProductMech

fujikurin D

CHEBI:156547 EXACT SEEDED

A pyrandione that is dihydro-2H-pyran-2,4(3H)-dione in which the hydrogens at positions 3, 5 and 6 are substituted by 1-hydroxy-2-methylbutylidene, methyl, and methyl groups, respectively. It is a natural product isolated from the fungus Fusarium fujikuroi.

Structure

Standard InChIKeyHRHXOJYXAMLRQF-MDZDMXLPSA-N
SMILESCCC(C)C(\O)=C1/C(=O)OC(C)C(C)C1=O
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA04349, pubchem:122183676

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Fusarium fujikuroi IMI 58289
NCBITaxon:1279085
SOURCE_ASSERTION mibig:BGC0001305 PMID:26192387

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Fusarium fujikuroi
NCBITaxon:5127
LOTUS DOI:10.1021/NP5008137
Fusarium fujikuroi
NCBITaxon:5127
CHEBI PMID:26192387

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001305 Fusarium fujikuroi IMI 58289
NCBITaxon:1279085
CLUSTER_UNSTATED genbank:HF679030.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001305MIBIG4
CHEBI:156547CHEBI3-star

This page is generated from data/natural_products/polyketides/fujikurin-d.yaml, which is generated from the committed inventories. Neither is edited by hand.