Fumonisin B1
naturalproductmech:mibig-5cf1186271 MINTED SEEDED
Structure
| Standard InChIKey | UVBUBMSSQKOIBE-NDFMDLIYSA-N |
|---|---|
| SMILES | CCCC[C@@H](C)[C@H]([C@H](C[C@@H](C)C[C@@H](CCCC[C@H](C[C@@H]([C@H](C)N)O)O)O)OC(=O)C[C@H](CC(=O)O)C(=O)O)OC(=O)C[C@H](CC(=O)O)C(=O)O |
| Stereochemistry | fully defined |
| Cross-references | npatlas:NPA012054 |
Filing pathway
Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.
Producer organisms 3
A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.
| Taxon | Basis | Cluster | Evidence |
|---|---|---|---|
| Fusarium fujikuroi NCBITaxon:5127 |
BGC_CORRELATED | mibig:BGC0002502 | PMID:30987138 |
| Fusarium verticillioides NCBITaxon:117187 |
SOURCE_ASSERTION | mibig:BGC0000062 | DOI:10.1006/fgbi.1999.1141 |
| Fusarium oxysporum NCBITaxon:5507 |
SOURCE_ASSERTION | mibig:BGC0000063 | DOI:10.1016/j.fgb.2008.02.004 |
Occurrences 3
Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.
| Taxon | Source | Reference |
|---|---|---|
| Fusarium verticillioides NCBITaxon:117187 |
LOTUS | DOI:10.1016/J.TOXICON.2010.04.008 |
| Fusarium fujikuroi NCBITaxon:5127 |
LOTUS | DOI:10.1016/J.TOXICON.2010.04.008 |
| Fusarium fujikuroi NCBITaxon:5127 |
LOTUS | DOI:10.1128/AEM.54.7.1806-1811.1988 |
Biosynthetic gene clusters 3
| Accession | Host | Locus evidence | Genome |
|---|---|---|---|
| mibig:BGC0002502 | Fusarium fujikuroi NCBITaxon:5127 |
CLUSTER_CORRELATED | genbank:HQ622717.1 |
| mibig:BGC0000062 | Fusarium verticillioides NCBITaxon:117187 |
CLUSTER_UNSTATED | genbank:AF155773.5 |
| mibig:BGC0000063 | Fusarium oxysporum NCBITaxon:5507 |
CLUSTER_UNSTATED | genbank:EU449979.1 |
A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.
Open questions 1
shared-structure — This structure is reported by more than one MIBiG entry: BGC0000062, BGC0000063, BGC0002502. Confirm they describe the same compound rather than an upstream cross-reference error.
Provenance
| Source concept | Source | Version |
|---|---|---|
| BGC0002502 | MIBIG | 3 |
| BGC0000062 | MIBIG | 4 |
| BGC0000063 | MIBIG | 3 |
This page is generated from data/natural_products/polyketides/fumonisin-b1.yaml, which is generated from the committed inventories. Neither is edited by hand.