NaturalProductMech

Fumonisin B3

naturalproductmech:mibig-08be9ef8b0 MINTED SEEDED

Structure

Standard InChIKeyCPCRJSQNWHCGOP-ZYKBYZIHSA-N
SMILESCCCC[C@@H](C)[C@H]([C@H](C[C@@H](C)C[C@@H](CCCCCC[C@@H]([C@@H](C)N)O)O)OC(=O)C[C@@H](CC(=O)O)C(=O)O)OC(=O)C[C@@H](CC(=O)O)C(=O)O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA008490

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, from MIBiG.

Producer organisms 2

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Fusarium fujikuroi
NCBITaxon:5127
BGC_CORRELATED mibig:BGC0002502 PMID:30987138
Fusarium verticillioides
NCBITaxon:117187
SOURCE_ASSERTION mibig:BGC0000062 DOI:10.1006/fgbi.1999.1141

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Fusarium fujikuroi
NCBITaxon:5127
LOTUS DOI:10.1021/JF070061H
Fusarium fujikuroi
NCBITaxon:5127
LOTUS DOI:10.3390/TOXINS11040200

Biosynthetic gene clusters 2

AccessionHostLocus evidenceGenome
mibig:BGC0002502 Fusarium fujikuroi
NCBITaxon:5127
CLUSTER_CORRELATED genbank:HQ622717.1
mibig:BGC0000062 Fusarium verticillioides
NCBITaxon:117187
CLUSTER_UNSTATED genbank:AF155773.5

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Open questions 1

shared-structure — This structure is reported by more than one MIBiG entry: BGC0000062, BGC0002502. Confirm they describe the same compound rather than an upstream cross-reference error.

Provenance

Source conceptSourceVersion
BGC0002502MIBIG3
BGC0000062MIBIG4

This page is generated from data/natural_products/polyketides/fumonisin-b3.yaml, which is generated from the committed inventories. Neither is edited by hand.