NaturalProductMech

germicidin

naturalproductmech:mibig-79ea2b2bbd MINTED SEEDED

Structure

Standard InChIKeyNPQKQKITPJTEBK-UHFFFAOYSA-N
SMILESCCC(C)C1=CC(O)=C(CC)C(=O)O1
Stereochemistry undefined stereocentres — the InChIKey does not distinguish this compound from its stereoisomers
Cross-referencesnpatlas:NPA010967

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is other, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces argillaceus
NCBITaxon:41951
SOURCE_ASSERTION mibig:BGC0001454 PMID:29795673

Occurrences 11

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1007/S00248-014-0508-0
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1007/S10295-013-1383-2
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1021/JA065247W
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.1038/JA.2011.59
Streptomyces albidoflavus
NCBITaxon:1886
LOTUS DOI:10.7164/ANTIBIOTICS.46.1126
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1007/S00248-014-0508-0
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1007/S10295-013-1383-2
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1021/JA065247W
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.1038/JA.2011.59
Streptomyces coelicolor
NCBITaxon:1902
LOTUS DOI:10.7164/ANTIBIOTICS.46.1126
Streptomyces argillaceus
NCBITaxon:41951
LOTUS DOI:10.1371/JOURNAL.PONE.0198145

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0001454 Streptomyces argillaceus
NCBITaxon:41951
CLUSTER_UNSTATED genbank:LT989884.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0001454MIBIG5

This page is generated from data/natural_products/polyketides/germicidin.yaml, which is generated from the committed inventories. Neither is edited by hand.