NaturalProductMech

grincamycin

naturalproductmech:mibig-083c304beb MINTED SEEDED

Structure

Standard InChIKeyJEMVIRAQUIJOCL-XURVNGJNSA-N
SMILESC[C@@H]1O[C@H](CC[C@@H]1O[C@H]1CCC(=O)[C@H](C)O1)O[C@@H]1[C@@H](C)O[C@H](C[C@H]1O)C1=CC=C2C(=O)C3=C(C=C[C@]4(O)C[C@](C)(CC(=O)[C@]34O)O[C@H]3CC[C@H](O[C@H]4CCC(=O)[C@H](C)O4)[C@H](C)O3)C(=O)C2=C1O
Stereochemistryfully defined
Cross-referencesnpatlas:NPA01972

Filing pathway

Polyketides — computed by NPClassifier npclassifier.gnps2.org@2026-09-07, which is why it is pinned rather than recomputed. The gene cluster's asserted class is pks, saccharide, from MIBiG.

Producer organisms 1

A claim that this taxon makes the compound. The basis says what the evidence addressed — a knockout and a database assertion are not the same claim.

TaxonBasisClusterEvidence
Streptomyces lusitanus
NCBITaxon:68232
BGC_CHARACTERIZED mibig:BGC0000229 PMID:23782455

Occurrences 2

Somebody found the compound in this organism and cited it. That is not a claim that the organism makes it, and nothing here promotes one to the other.

TaxonSourceReference
Streptomyces griseoincarnatus
NCBITaxon:29305
LOTUS DOI:10.7164/ANTIBIOTICS.40.1785
Streptomyces lusitanus
NCBITaxon:68232
LOTUS DOI:10.1021/NP2008335

Biosynthetic gene clusters 1

AccessionHostLocus evidenceGenome
mibig:BGC0000229 Streptomyces lusitanus
NCBITaxon:68232
CLUSTER_DEMONSTRATED genbank:KC962511.1

A locus claim and a taxon claim are different questions. Heterologous expression settles the first and leaves the second where the isolation report left it.

Provenance

Source conceptSourceVersion
BGC0000229MIBIG5

This page is generated from data/natural_products/polyketides/grincamycin.yaml, which is generated from the committed inventories. Neither is edited by hand.